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A change in the axon membrane potential from -70 mV to -90 mV would be termed a(n)


A) depolarization.
B) threshold potential.
C) action potential.
D) hyperpolarization.
E) excitatory local potential.

F) B) and C)
G) B) and E)

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Which of the following structures is the site of production of proteins?


A) vesicles
B) ribosomes
C) genes
D) myeline
E) the nucleolus

F) A) and B)
G) C) and D)

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The primary symptom shown by Kathryn D. was


A) severe nausea.
B) inability to sleep.
C) muscle weakness.
D) distortions of memory.
E) difficulty in recognizing facial displays of emotion.

F) C) and D)
G) B) and D)

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___________ are multi-function glial cells that participate in phagocytosis, provide lactate for cells, and structurally support neurons in the brain.


A) Schwann
B) Astrocytes
C) Microglia
D) Oligodendrocytes
E) Microtubules

F) B) and C)
G) C) and D)

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Nerve cells are able to rapidly metabolize fuel because


A) of their capacity to store glucose in the cytoplasm.
B) neurons receive lactate from astrocytes.
C) glial cells can transfer ATP into neurons.
D) brain blood vessels can convert glucose into lactate for neuron use.
E) glial cell mitochondria process fuel for the neuron.

F) B) and C)
G) B) and D)

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Which of the following is correct regarding axoplasmic transport?


A) The dynein molecule is involved in anterograde axoplasmic transport.
B) Retrograde axoplasmic transport involves moving substances from the soma to the axon terminals.
C) The kinesin molecule is involved in retrograde axoplasmic transport.
D) Retrograde transport is half as fast as anterograde axoplasmic transport.
E) Transport of materials occurs only in one direction.

F) B) and E)
G) C) and E)

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Sodium ions move out of the axon because of


A) the opening of sodium channels.
B) the opening of voltage-gated channels.
C) kinesin.
D) electrostatic pressure.
E) the sodium-potassium transporter.

F) A) and B)
G) None of the above

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Autoreceptors are located on the ___________.


A) Golgi apparatus
B) presynaptic membrane
C) endoplasmic reticulum
D) postsynaptic membrane
E) mitochondria

F) A) and B)
G) A) and E)

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Action potentials are generated at the _______ and are conducted along the _______.


A) axon hillock; axon
B) axon; dendrite
C) terminal buttons; dendrite
D) dendrite; glial membrane
E) axon button; glial membrane

F) A) and D)
G) A) and E)

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Regrowth of a damaged axon can occur more readily in the peripheral nervous system than in the brain because


A) Schwann cells form barriers to axon regrowth.
B) Schwann cells form cylinders through which new axons can grow and reinnervate a target cell nerve cell.
C) Schwann cells generate a chemical signal that instructs nerve cells to die.
D) Astrocytes form cylinders through which new axons can grow and reinnervate a target cell nerve cell.
E) Oligodendroglia form barriers to axon regrowth.

F) B) and C)
G) None of the above

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In order to produce a depolarization or hyperpolarization of the postsynaptic membrane, neurotransmitters


A) diffuse widely in the brain to exert changes in metabolism.
B) act through ionotropic receptors to activate a second-messenger.
C) are released into the synapse from the cisternae.
D) open ion channels in the postsynaptic membrane.
E) alter ion channel activity for minutes.

F) C) and D)
G) A) and B)

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Match up the correct receptor type and effect.


A) metabotropic; direct opening of an ion channel
B) ionotropic; more time required to open an ion channel
C) metabotropic; G protein activation leads to activation of a second-messenger
D) metabotropic; rapid opening of a single ion channel
E) metabotropic; rapid short-lived effects on ion channels

F) A) and B)
G) B) and E)

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Sodium ions will be pushed into a resting neuron by the forces of


A) inactivation of potassium channels; diffusion.
B) electrostatic pressure; sodium-potassium pump activation.
C) sodium-potassium pump activation; diffusion.
D) ion channel inactivation; diffusion.
E) diffusion; electrostatic pressure.

F) B) and C)
G) B) and E)

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Explain why the termination step of the neural communication process is a key target for therapeutic drugs.

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The postsynaptic action of many neurotra...

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Explain how changes in ion movements can result in an action potential.

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At rest, the interior of the axon membra...

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Motor neurons control the activity of the ________.

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Which of the following was suggested as an advantage associated with myelination?


A) Myelin changes the height of the action potential.
B) Myelin increases the energy requirements of the nerve cell.
C) Myelin slows down conduction speed.
D) Myelin reduces the threshold for induction of an action potential.
E) Myelin speeds up axon conduction speed.

F) B) and C)
G) B) and E)

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Match the correct function with the neuronal organelle.


A) mitochondria; production of fat-like molecules
B) mitochondria; formation of vesicles
C) endoplasmic reticulum; breakdown of proteins
D) microtubules; transport of molecules between the soma and the axon terminals
E) Golgi apparatus; extraction of energy for cell use

F) None of the above
G) A) and C)

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_______ are located only within the central nervous system.


A) Sensory
B) Motor
C) Relay interneurons
D) Projection neurons
E) Schwann cells

F) B) and D)
G) C) and D)

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Which of the following is an important advantage associated with saltatory conduction?


A) More sodium ions have to be pumped out of the cell after an action potential.
B) Myelin allows the nerve cell to recycle neurotransmitter molecules.
C) Less transmitter is required to send a message across the next synapse.
D) Myelin speeds up the velocity at which an axon can conduct an action potential.
E) Myelin requires that nerve cell axons be larger in order to conduct a signal rapidly.

F) A) and E)
G) A) and D)

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